Vol. 34, Nš 3

Treatments used in menopausal women susceptible to dyslipidemia and diabetes

VELOSO, A. G. B.; GAMA, E. F.; MAIFRINO, L. B. M.

KEYWORDS: pancreas, dyslipidemia and diabetes, physical exercise, treatment.

ABSTRACT: Objective: The objective of this study was to investigate the efficacy of types of treatment most used in menopausal women with dyslipidemia and susceptible to insulin resistance. Material and Methods: In the period between 2006 and 2016, articles of the PubMed database were evaluated using the keywords: pancreas, menopause, dyslipidemia and treatment. The following parameters were evaluated: title, year of publication, author, country of origin, studied model (human or animal), types of analysis (biometric, biochemical, physiological, morphological and immunohistochemical). Results: Of 530 articles investigated, 11 were evaluated, among which 45% used physical exercise as a treatment, 37% used the pharmacological treatment and 18% used diet. As for the year and country where the study was performed, 73% of the articles were published in the last six years (2011-2016), and 73% were published in the United States. In 27.3% of the articles were used animal models, and 72.7% used human models. The most employed analysis in the studies was the biochemical, and the least used (5%) was the morphological. Conclusion: Although physical exercise was the most common treatment in this study, the other treatments (diet and drugs) are of paramount importance to prevent pancreatic diseases and the development of type 2 diabetes, which certainly trigger a clinical picture of dyslipidemia, resulting in the irreversible deterioration of pancreatic cells.